Dr. Surabhi Chandra

Associate Professor

Office: BHS 201B   |    Phone: (308) 865-8695   |    Email: chandras2@unk.edu

Dr. Surabhi Chandra


Areas of Interest:

  • Cardiovascular and renal physiology
  • Pharmacology


  • B.S. (2001) - University of Mumbai, India
  • M.S. (2003) - University of Mumbai, India
  • PhD. (2008) - Tulane University

Professional Affiliations:


  • Chandra, S.  2008.  Investigations on the molecular mechanisms of HIV-1 protease inhibitor induced insulin resistance:  protection by thymoquinone.  Ph. D. Dissertation, Tulane University, New Orleans.


  • Way, H., Roh, J., Venteicher, B., Chandra, S., and Thomas, A.A.  2022.   Synthesis of ribavirin 1,2,3- and 1,2,4-triazolyl analogs with changes at the amide and cytotoxicity in breast cancer cell lines.  Nucleosides, Nucleotides & Nucleic Acids  https://doi.org/10.1080/15257770.2022.2107218
  • Capellen, C.C., Ortega-Rodas, J., Morwitzer, M.J., Tofilau, H.M.N., Dunworth, M., Casero, R.A. Jr., Chandra, S.  2021.  Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase.  Breast Cancer Res Treat. 190(2):255-264.  doi: 10.1007/s10549-021-06388-0.  Epub 2021 Sep 16. PMID: 34529197 
  • Hamilton, L. J., Walker, M., Pattabiraman, M., Zhong, H. A., Luedtke, B., and Chandra, S.  2021.  Novel curcumin analog (cis-trans curcumin) as ligand to adenosine receptors A2A and A2B: potential for therapeutics. Pharmacological Research online.
  • Dutta, D., Palmer, X-L., Ortega-Rodas, J., Balraj, V., Dastider, I. G., and Chandra, S.  2020.  Biomechanical and biophysical properties of breast cancer cells under varying glycemic regimens.  Breast Cancer: Basic and Clinical Research 14:1-6. 
  • Carlson, D., Chandra, S., Hobbs, N., and Steele, J.  2019.  Clay modeling in a sophomore-level anatomy laboratory:  Will active learning improve student performance?  Human Anatomy & Physiology Society (HAPS) Educator 23:5-11. 
  • Dutta, D., Russell, C., Kim, J., and Chandra, S.  2018.  Differential mobility of breast cancer cells and normal breast epithelial cells under dc electrophoresis and electroosmosis.  Anticancer Research 38: 5733-5738.
  • Priebe, A., Hunke, M., Tonello, R., Sonawane, Y., Berta, T., Natarajan, A., Bhuvanesh, N., Pattabiraman, M., and Chandra, S.  2018.  Ferulic acid dimer as a non-opioid therapeutic for acute pain.  Journal of Pain Research 11:1075-1085.
  • Hunke, M., Martinez, W., Kashyap, A., Bokoskie, T., Pattabiraman, M., and Chandra, S.  2018.  Antineoplastic actions of cinnamic acids and their dimers in breast cancer cells: A comparative study.  Anticancer Research 38(8):4469-4474.
  • Yao, L., Chandra, S., Toque, H. A., Bhatta, A. and Caldwell, R. W.  2013. Prevention of diabetes induced arginase activation and endothelial dysfunction by Rho kinase knockout.  Cardiovascular Research 97(3):509-19.
  • Chandra, S., Romero, M. J., Shatanawi, A., Alkilany, A., Caldwell, R. B., and Caldwell, R. W.  2012.  Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway.  British Journal of Pharmacology 165(2):506-19.
  • Shatanawi, A., Romero, M. J., Iddings, J. A., Chandra, S., Umapathy, N. S., Verin, A. D., Caldwell, R. B., and Caldwell, R. W.  2011.  Angiotensin II increases arginase activity and expression through RhoA/Rho kinase and p38 mitogen-activated protein kinase (MAPK) pathways  American Journal of Physiology-Cell Physiology 300(5):C1181-92.
  • Datar, R., Kaesemeyer, W. H., Chandra, S., Fulton, D. J., and Caldwell, R. W.  2010.  Acute activation of eNOS by lovastatin involves scavengerreceptor-B1, G protein subunit Gi, phospholipase C, and calcium influx.  British Journal of Pharmacology 160 (7):1765-1772.
  • Toque, H. A., Romero, M. J., Tostes, R. C., Shatanawi, A., Chandra, S., Carneiro, Z., Inscho, E., Webb, R. C., Caldwell, R. B., and Caldwell, R. W.  2010.  p38 mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II treated mice.  Journal of Sexual Medicine 7(12):3857-67.
  • Gur, S., Kadowitz, P. J., Gurkan, L., Chandra, S., DeWitt, S. Y., Harbin, A., Sikka, S. C. and Hellstrom, W. J. G.  2010.  Chronic inhibition of nitric oxide synthase induces hypertension and erectile dysfunction in the rat that is not reversed by sildenafil.  British Journal of Urology 106 (1):78-83.
  • Chandra, S., Murthy, S. N., Mondal, D. and Agrawal, K. C.  2009.  Therapeutic effects of black seed oil (Nigella sativa) on chronic HAART exposure induced hyperinsulinemia in rats Canadian Journal of Physiology and Pharmacology 87 (4):300-9.
  • Chandra, S., Mondal, D. and Agrawal, K. C.  2009.  HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release from pancreatic beta-cells: protective effect of thymoquinone.  Experimental Biology and Medicine 234 (4):442-53.
  • Murthy, S.N., Sukhanov, S., McGee, J., Greco, A. J., Chandra, S., Delafontaine, P., Kadowitz, P. J., McNamara, D. B. and Fonseca, V. A.  2009.  Insulin Glargine reduces carotid intimal hyperplasia after balloon catheter injury in Zucker fatty rats possibly by reduction in oxidative stress.  Molecular and Cellular Biochemistry 330 (1-2):1-8.
  • Pradhan, L., Mondal, D., Chandra, S., Ali, M. and Agrawal, K. C.  2008.  Molecular analysis of cocaine-induced endothelial dysfunction: role of endothelin-1 and nitric oxide.  Cardiovascular Toxicology 8 (4):161-71.
  • Gur, S., Sikka, S. C., Chandra, S., Koka, P. S., Agrawal, K. C., Kadowitz, P. J. and Hellstrom, W. J. G.  2008.  Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction.  British Journal of Urology 102 (11):1651-7.
  • Kendirci, M., Pradhan, L., Trost, L., Gur, S., Chandra, S., Agrawal, K. C. and Hellstrom, W. J. G.  2007.  Peripheral mechanisms of erectile dysfunction in a rat model of chronic cocaine use.  European Urology 52(2):555-64.