Dr. Kim Carlson


Office: BHS 223   |    Phone: (308) 865-1554   |    Email: carlsonka1@unk.edu

Dr. Kim Carlson


Advisor for Molecular Biology Comprehensive Major

Areas of Interest:

  • Aging research, OTK18 gene, Nora virus



  • Ikezu, T., Leisman, G. D., Carlson, K. A., and Gendelman, H. E. 2006. Antibodies specific for NEBR1 and methods of use thereof. US Patent #7,074,554. (July 2006).
  • Ikezu, T., H. E. Gendelman, K. A. Carlson, & G. D. Leisman. 2004. Methods and compositions for the treatment of human immunodeficiency virus infection. US Patent #6,689,877. (February 2004)

Professional Affiliations:

Dissertation and Thesis:

  • Carlson, K. A. 1998. Analysis of reproduction in extended longevity lines of Drosophila melanogaster. Ph. D. Dissertation, University of Nebraska - Lincoln. 159 pp.
  • Smith, K. A. 1994. A molecular analysis of the retinoblastoma gene in Oryzias latipes. M.S. Thesis, University of Nebraska at Kearney. 45 pp.


  • Rokusek, B.S., Cheku, S., Rokusek, M., Waples, C.J., Harshman, L., and Carlson, K.A.  2023.  HoTDAM! An easy-to-use automated assay expands the inducible thermotolerance phenotype in Drosophila melanogaster: heat hardening reduces motility.  Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology 286:111522.  https://doi.org/10.1016/j.cbpa.2023.111522
  • Buhlke, E.G., Hobbs, A.M., Rajput, S., Rokusek, B., Carlson, D.J., Gillan, C., and Carlson, K.A.  2022.  Characterization of cross-species transmission of Drosophila melanogaster Nora virus.  Life 12(11), 1913.  doi: 10.3390/life12111913 
  • Carter, Z., Peterson, B.C., Schoenebeck, C.W., and Carlson, K.A.  2022.  Genetic protocols for DNA extraction from white-tailed deer cast antlers to confirm individuality.  Transactions of Nebraska Academy of Sciences 42:15-22.
  • Licking-Murray, K.D., Carlson, D.J., Sowle, R., and Carlson, K.A.  2021.  In vitro assembly and evaluation of Nora virus VLPs.  Acta Virologica 65:381-389.  doi: 10.4149/av_2021_403
  • Hobbs, A.M., Kluthe, K.E., Carlson, K.A., and Nuxoll, A.S.  2021.  Interruption of the tricarboxylic acid cycle in Staphylococcus aureus leads to increased tolerance in innate immunity.  AIMS Microbiology 7(4):513-527.  doi: 10.3934/microbiol.2021031
  • Moghe, S., Baumgart, K., Shaffer, J.J., and Carlson, K.A.  2021.  Female mentors positively contribute to undergraduate STEM research experiences.  PLOS One  https://doi.org/10.1371/journal.pone.0260646
  • Schissel, M., Best, R., Liesemeyer, S., Tan, Y-D., Carlson, D.J., Shaffer, J.J., Avuthu, N., Guda, C., and Carlson, K.A.  2021.  Effect of Nora virus infection on native gut bacterial communities of Drosophila melanogaster.  AIMS Microbiology 7(2):216-237.  doi:  10.3934/microbiol.2021014
  • Macke, A., Lopez, W., Carlson, D.J., and Carlson, K.A.  2020.  Nora virus VP4b and ORF1 circulate in hemolymph of infected D. melanogaster with coordinate expression of vago and vir-1.  Vaccines 8(3)  doi:  doi.org/10.3390/vaccines8030491
  • Everitt, K.R., Schmitz, H.C., Macke, A., Shan, J., Jang, E., Luedtke, B.E., Carlson, K.A., and Cao, H.  2020.  Investigation of a sensing strategy based on a nucleophilic addition reaction for quantitative detection of bisulfite (HSO3-).  Journal of Fluorescence Sep;30(5):977-983.  doi: 10.1007/s10895-020-02599-8   
  • Rogers, A., Towery, L., McCown, A., and Carlson K.A.  2020.  Impaired geotaxis as a novel phenotype of nora virus infection of Drosophila melanogaster.  Scientifica  doi:  doi.org/10.1155/2020/1804510
  • Schoenebeck, C.W., Prenosil, E., Pallas, B., Abrams, A., and Carlson, K.  2018.  Can lactate dehydrogenase be used to index anaerobic activity in fishes?  Transactions of the Nebraska Academy of Sciences and Affiliated Societies 38:26-29.
  • Lopez, W.A., Page, A.M., Ericson, B.L., Carlson, D.J., and Carlson, K.A.  2018.  Chapter 12 - Antiviral immunity in the fruit fly, Drosophila melanogaster.  Drosophila melanogaster - Model for Recent Advances in Genetics and Therapeutics, Intech.  doi:  10.5772/intechopen.69293 
  • Lopez, W., Page, A.M., Carlson, D.J., Ericson, B.L., Cserhati, M.F., Guda, C., and Carlson, K.A.  2018.  Analysis of immune-related genes during nora virus infection of Drosophila melanogaster using next generation sequencing.  AIMS Microbiology 4(1):123-139.
  • Kim, G., Jang, E., Page, A.M., Ding, T., Carlson, K.A., and Cao, H.  2016.  Investigation of a sensing approach based on a rapid reduction of azide to selectively measure bioavailability of H2S.  RSC Adv.  6:95920-95924.
  • Carlson, K.A., Zhang, C., and Harshman, L.G.  2016.  A dataset for assessing temporal changes in gene expression during the aging process of adult Drosophila melanogaster.  Data Brief 7:1652-7; doi: 10.1016/j.dib.2016.04.072.
  • Ericson, B.L., Carlson, D.J., and Carlson, K.A.  2016.  Characterization of nora virus structural proteins via western blot analysis.  Scientifica Virologica doi: 10.1155/2016/9067848.
  • Munn, B., Ericson, B., Carlson D.J., and Carlson, K.A.  2015.  Detecting the presence of nora virus in Drosophila utilizing single fly RT-PCR.  Bioscene: Journal of College Science Teaching 41(2):40-44.
  • Carlson K.A., Gardner K., Pashaj A., Carlson D.J., Yu F., Eudy J.D., Zhang C., and Harshman L.G.  2015.  Genome-Wide Gene Expression in relation to Age in Large Laboratory Cohorts of Drosophila melanogaster.  Genetics Research International  Epub May 21.
  • Weatherred, W., Carlson, D.J., Carlson, K.A. 2014. Nora virus transmission in Drosophila melanogaster: an investigation to teach viral infection and prophylaxis to biology students.  Bioscene: Journal of College Science Teaching 40(1):11-15.
  • Cordes, E. J., Licking, K. D., and Carlson, K. A. 2013. Differential gene expression related to Nora virus infection of Drosophila melanogaster.  Virus Research 175:95-100.
  • Billingsley, J., and Carlson, K. A. 2010. Epigenetic effects of diet on fruit fly lifespan: an investigation to teach epigenetics to biology students.  American Biology Teacher 72(4):231-234.
  • Gilling, C. E., and Carlson, K. A. 2009. The effect of OTK18 upregulation in U937 cells on neuronal survival.  In Vitro Cellular & Developmental Biology - Animal 45:243-251.
  • Carlson, D. J., Pashaj, A., Gardner, K., and Carlson, K. A. 2008. Advances in age old questions. Fly 2(3):149-151.
  • Derr, J. N., Smith, T. L., and Carlson, K.A. 2008. Effects of blueberries on mortality rates and Indy gene expression in Drosophila melanogaster.  Transactions of the Nebraska Academy of Sciences 31:61-67
  • Larson, S. L., Gilling, C. E., and Carlson, K. A. 2008. A proposed mechanism for OTK18 regulation of TNF-α in response to neurotoxic insult.  Journal of Biology, Biological Systems, and Bioinformatics 2(1).
  • Spresser, C. R., Marshall, S., and Carlson, K. A. 2008. Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity.  Journal of Genetics 87:109-117.
  • Wagoner, S., and Carlson, K. A. 2008. DNA fingerprinting in a forensic teaching experiment.  American Biology Teacher 70(6):29-33.
  • Wollard, L., Klein, B., Carlson, D. J., and Carlson, K. A. 2006. Rearing mediums as a variable in fruit fly fecundity: an activity to introduce scientific methods of inquiry to biology students.  Bioscene: Journal of College Science Teaching. 32(3):24-29.
  • Spresser, C. R. & K. A. Carlson. 2005. Drosophila melanogaster as a complementary system for studying HIV-1 related genes and proteins.  Journal of Neuroscience Research 80(4):451-455.
  • Wojna, V., Carlson, K. A., Xiaoguang, L., Mayo, R., Meléndez, L. M., Kraiselburd, E., and Gendelman, H. E. 2004. Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: a case study.  Journal of Neurovirology 10:74-81. (Considered to be a co-senior-authored paper by the journal)
  • Carlson, K. A., Leisman, G., Limoges, J., Pohlman, G. D., Horiba, M., Buescher, J., Gendelman, H. E., & Ikezu, T. 2004.  Molecular characterization of a putative antiretroviral transcriptional factor, OTK18.  Journal of Immunology  172:381-391.
  • Carlson, K. A., Limoges, J., Pohlman, G. D., Poluektova, L. Y., Langford, D., Masliah, E., Ikezu, T., & Gendelman, H. E. 2004. OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis.  Journal of Neuroimmunology 150:186-198.
  • Carlson, K. A., Ciborowski, P., Schellpeper, C. N., Biskup, T. M., Shen, R.-F., Luo, X., Destache, C. J., & Gendelman, H. E. 2004. Proteomic fingerprinting of HIV-1-infected human monocyte-derived macrophages: a preliminary report.  Journal of Neuroimmunology 147:35-42.
  • Xiong, H., Boyle, J., Winkelbauer, M., Gorantla, S., Zheng, J., Ghorpade, A., Persidsky, Y., Carlson, K. A., & Gendelman, H. E.2003. Inhibition of long-term potentiation by Interleukin-8: implications for human immunodeficiency virus-1-associated dementia.  Journal of Neuroscience Research 71(4):600-607.
  • Gendelman, H. E., Destache, C. J., Zelivyanskaya, M. L., Nelson, J. A., Boska, M. D., Biskup, T. M., McCarthy, M. K., Carlson, K. A., Nemechek, C., Benner, E. J., & Mosley, R. L. 2003. Neuroimaging and proteomic tracking of neurodegeneration in MPTP-treated mice.  Annals of the New York Academy of Sciences 991:319-321.
  • Luo, X., Carlson, K. A., Wojna, V., Mayo, R., Biskup, T. M., Stoner, J., Anderson, J., Gendelman, H. E., & Melendez, L. M. 2003. Macrophage proteomic fingerprinting predicts HIV-1-associated cognitive impairment.  Neurology 60(12):1931-1937.
  • Shibata, A., Zelivyanskaya, M., Limoges, J., Carlson, K. A., Gorantla, S., Branecki, C., Bishu, S., Xiong, H., & Gendelman, H. E. 2003. Peripheral nerve induces macrophage neurotrophic activities: regulation of neuronal process outgrowth, intracellular signaling and synaptic function.  Journal of Neuroimmunology 142:112-129.
  • Carlson, K. A., Cotter, R. L., Williams, C. E., Branecki, C. E., & Gendelman, H. E. 2002. The role of mononuclear phagocytes in the pathogenesis of Alzheimer's disease.  In TheMacrophage, 2nd Edition (edited by B. Burke & C. Lewis). Oxford, England: Oxford Medical Publications.
  • Carlson, K. A., & Harshman, L. G. 1999. Extended longevity lines of Drosophila melanogaster: abundance of yolk protein gene mRNA in fat body and ovary.  Experimental Gerontology 34:173-184.
  • Carlson, K. A., & Harshman, L. G. 1999. Extended longevity lines of Drosophila melanogaster: characterization of oocyte stages and ovariole numbers as a function of age and diet.  Journals of Gerontology. Series A: Biological and Medical Sciences 54(10):B432-440.
  • Carlson, K. A., Nusbaum, T. M., Rose, M. R., & Harshman, L. G. 1998. Oocyte maturation and ovariole number in lines of Drosophila melanogaster selected for postponed senescence.  Functional Ecology 12(4):514-520.