Dr. Austin Nuxoll
Associate Professor, Graduate Program Chair (Biology MS - Non-Thesis)
Office:
BHS
201D |
Phone: (308) 865-8602 |
Email: nuxollas@unk.edu
Biography
Areas of Interest:
- Microbial Pathogenesis, Host-Pathogen Interactions, Antibiotic Tolerance
Degrees:
Professional Affiliations:
Dissertation:
- Nuxoll, A. S. 2009. Arginine Biosynthesis in Staphylococcus aureus. Ph. D. Dissertation, University of Nebraska Medical Center, Omaha, Nebraska. 193 pp.
Publications:
- Hobbs, A.M., Kluthe, K.E., Carlson, K.A., and Nuxoll, A.S. 2021. Interruption of the tricarboxylic acid cycle in Staphylococcus aureus leads to increased tolerance in innate immunity. AIMS Microbiology 7(4):513-527. doi: 10.3934/microbiol.2021031
- Nabb, D.L., Song, S., Kluthe, K.E., Daubert, T.A., Luedtke, B.E., Nuxoll, A.S. 2019. Polymicrobial interactions induce multidrug tolerance in Staphylococcus aureus through energy depletion. Frontiers in Microbiology 10(2803).
- Zalis, E.A., Nuxoll, A.S., Manuse, S., Clair, G., Radlinski, L.C., Conlon, B.P., Adkins, J., Lewis, K. 2019. Stochastic variation in expression of the tricarboxylic acid cycle produces persister cells. mBio 10:e01930-19.
- Halsey, C.R., Lei, S., Wax, J.K., Lehman, M.K., Nuxoll, A.S., Steinke, L., Sadykov, M., Powers, R., and Fey, P.D. 2017. Amino acid catabolism in Staphylococcus aureus and the function of carbon catabolite repression. mBio 8(1) pii: e01434-16.
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Homma, T., Nuxoll, A., Brown-Gandt, A., Ebne,r P., Engels, I., Schneider, T., Gotz, F., Lewis, K., and Conlon, B. P. 2016. Dual targeting of cell wall precursors by teixobactin leads to cell lysis. AAC doi: 10.1128/ AAC.01050-16 AAC.01050-16.
- Conlon, B.P., Rowe, S.E., Gandt, A.B., Nuxoll, A.S., Donegan, N.P., Zalis, E.A., Clair, G., Adkins, J.N., Cheung, A.L., and Lewis, K. 2016. Persister formation in Staphylococcus aureus is associated with ATP depletion. Nat Microbiol doi: 10.1038/nmicrobiol.2016.51
- Lindgren, J.K., Thomas, V.C., Olson, M.E., Chaudhari, S.S., Nuxoll, A.S., Schaeffer, C.R., Lindgren, K.E., Jones, J., Zimmerman, M.C., Dunman, P.D., Bayles, K.W., and Fey, P.D. 2014. Arginine deiminase in Staphylococcus epidermidis functions to augment biofilm maturation through pH homeostasis. J Bacteriol 196(12): 2277-89.
- Gries, C.M., Bose, J.L., Nuxoll, A.S., Fey, P.D., and Bayles, K. W. 2013. The Ktr potassium transport system in Staphylococcus aureus and its role in cell physiology, antimicrobial resistance, and pathogenesis. Mol Micro 89(4): 760-73.
- Maliszewski, K.L., Nuxoll, A.S. 2013. Use of electroporation and conjugative mobilization for genetic manipulation of Staphylococcus epidermidis. Methods Mol Biol 1106: 125-134.
- Sadykov, M.R., Thomas, V.C., Marshall, D.D., Wenstrom, C.J., Moormeier, D.E., Widhelm, T.J., Nuxoll, A.S., Powers, R., and Bayles, K. W. 2013. Inactivation of the Pta-AckA pathway causes cell death in Staphylococcus aureus. J Bacteriol. 195(13): 3035-44.
- Nuxoll, A.S., Halouska, S.M., Sadykov, M.R., Hanke, M.L., Bayles, K.W., Kielian, T., Powers, R., and Fey, P.D. 2012. CcpA regulates arginine biosynthesis in Staphylococcus aureus through repression of proline catabolism. Plos Pathog 8(11): e1003033.