Dr. Austin Nuxoll

Associate Professor

Office: BHS 201D   |    Phone: (308) 865-8602   |    Email: nuxollas@unk.edu

Dr. Austin Nuxoll


Areas of Interest:

  • Microbial Pathogenesis, Host-Pathogen Interactions, Antibiotic Tolerance


Professional Affiliations:


  • Nuxoll, A. S. 2009. Arginine Biosynthesis in Staphylococcus aureus. Ph. D. Dissertation, University of Nebraska Medical Center, Omaha, Nebraska.  193 pp.


  • Hobbs, A.M., Kluthe, K.E., Carlson, K.A., and Nuxoll, A.S.  2021.  Interruption of the tricarboxylic acid cycle in Staphylococcus aureus leads to increased tolerance in innate immunity.  AIMS Microbiology 7(4):513-527.  doi: 10.3934/microbiol.2021031
  • Nabb, D.L., Song, S., Kluthe, K.E., Daubert, T.A., Luedtke, B.E., Nuxoll, A.S.  2019.  Polymicrobial interactions induce multidrug tolerance in Staphylococcus aureus through energy depletion.  Frontiers in Microbiology 10(2803).
  • Zalis, E.A., Nuxoll, A.S., Manuse, S., Clair, G., Radlinski, L.C., Conlon, B.P., Adkins, J., Lewis, K.  2019.  Stochastic variation in expression of the tricarboxylic acid cycle produces persister cells.  mBio 10:e01930-19.
  • Halsey, C.R., Lei, S., Wax, J.K., Lehman, M.K., Nuxoll, A.S., Steinke, L., Sadykov, M., Powers, R., and Fey, P.D.  2017.   Amino acid catabolism in Staphylococcus aureus and the function of carbon catabolite repression.  mBio  8(1) pii: e01434-16.
  • Homma, T., Nuxoll, A., Brown-Gandt, A., Ebne,r P., Engels, I., Schneider, T., Gotz, F., Lewis, K., and Conlon, B. P.  2016.  Dual targeting of cell wall precursors by teixobactin leads to cell lysis.  AAC  doi: 10.1128/ AAC.01050-16 AAC.01050-16.
  • Conlon, B.P., Rowe, S.E., Gandt, A.B., Nuxoll, A.S., Donegan, N.P., Zalis, E.A., Clair, G., Adkins, J.N., Cheung, A.L., and Lewis, K.  2016.  Persister formation in Staphylococcus aureus is associated with ATP depletion.  Nat Microbiol  doi: 10.1038/nmicrobiol.2016.51
  • Lindgren, J.K., Thomas, V.C., Olson, M.E., Chaudhari, S.S., Nuxoll, A.S., Schaeffer, C.R., Lindgren, K.E., Jones, J., Zimmerman, M.C., Dunman, P.D., Bayles, K.W., and Fey, P.D.  2014.   Arginine deiminase in Staphylococcus epidermidis functions to augment biofilm maturation through pH homeostasis.   J Bacteriol 196(12): 2277-89.
  • Gries, C.M., Bose, J.L., Nuxoll, A.S., Fey, P.D., and Bayles, K. W.  2013.  The Ktr potassium transport system in Staphylococcus aureus and its role in cell physiology, antimicrobial resistance, and pathogenesis.  Mol Micro 89(4): 760-73.
  • Maliszewski, K.L., Nuxoll, A.S.  2013.  Use of electroporation and conjugative mobilization for genetic manipulation of Staphylococcus epidermidis.  Methods Mol Biol 1106: 125-134.
  • Sadykov, M.R., Thomas, V.C., Marshall, D.D., Wenstrom, C.J., Moormeier, D.E., Widhelm, T.J., Nuxoll, A.S., Powers, R., and Bayles, K. W.  2013.  Inactivation of the Pta-AckA pathway causes cell death in Staphylococcus aureus.  J Bacteriol. 195(13): 3035-44.
  • Nuxoll, A.S., Halouska, S.M., Sadykov, M.R., Hanke, M.L., Bayles, K.W., Kielian, T., Powers, R., and Fey, P.D.  2012.   CcpA regulates arginine biosynthesis in Staphylococcus aureus through repression of proline catabolism.  Plos Pathog 8(11): e1003033.