University of Nebraska Kearney

Dr. Travis Bourret

Areas of Interest:

•  Lyme disease, Salmonella pathogenesis, nitric oxide, and oxidative stress 

                      Rank:  Assistant Professor        Year Hired:  2012

                     Office:  239

 

                     Phone:  (308) 865-8224

                     FAX:  (308) 865-8045

                     email:  bourrett@unk.edu
 

To see Dr. Bourret’s personal page click here. 

 

Advisor to Public Health Minor

Degrees:

Dissertation:

• Bourret, T.  2008.  The PhoPQ two-component regulatory system: At the crossroads of nitrosative stress and Salmonella pathogenesis.  Ph. D. Dissertation, University of Colorado Health Sciences Center, .

Publications:

• Bourret, T. J., Boylan, J. A., Lawrence, K. A., and Ghererdini, F.C.  2011.  Nitrosative damage to free and zinc-bound cysteine thiols underlies nitric oxide toxicity in wild-type Borrelia burgdorferi.  Molecular Microbiology 81(1):  259-273.

• Henard, C. A., Bourret, T. J., Song, M., and Vazquez-Torres, A.  2010.  Control of redox balance by the stringent response regulatory protein promotes antioxidant defenses of Salmonella.  J Biol Chem. 285(47):  36785-93.

• Husain, M., Jones-Carson, J., Song, M., McCollister, B. D., Bourret, T. J., Vazquez-Torres, A.  2010.  Redox sensor SsrB Cys203 enhances Salmonella fitness against nitric oxide generated in the host immune response to oral infection.  Proc Natl Acad Sci USA 107(32):  14396-401.
• Bourret, T. J., Song, M., and Vazquez-Torres, A.  2009.  Nitric oxide-mediated suppression of PhoPQ and SPI2 codependent and independent intracellular Salmonella enterica serovar Tryphimurium fitness.  Infect Immun 77(11):  5170-15.
• Bourrett, T. J., Porwollik, S., McClelland, M., Zhao, R., Greco, T., Ischiropoulos, H., and Vazquez-Torres, A.  2008.  Nitric oxide antagonizes the acid tolerance response that protects Salmonella against innate gastric defenses.  PLoS One 19;3(3):  e1833.
• Husain, M., Bourret, T. J., McCollister, B. D., Jones-Carson, J., Laughlin, J., and Vazquez-Torres, A.  2008.  Nitric oxide evokes an adaptive response to oxidative stress by arresting respiration.  J Biol Chem. 283(12):  7682-9.
• McCollister, B. D., Myers, J. T., Jones-Carson, J., Husain, M., Bourret, T. J., and Vazquez-Torres, A.  2007.  N₂O₃ enhances the nitrosative potential of IFN γ-primed macrophages in response to Salmonella.  Immunobiology 212(9-10):  759-69.
• McCollister, B. D., Bourret, T. J., Gill, R., Jones-Carson, J., and Vazquez-Torres, A.  2005.  Repression of SPI2 transcription by nitric oxide-producting, IFN γ-activated macrophages promotes maturation of Salmonella phagosomes.  J Exp Med. 202(5):  625-35.
   

Professional Affiliations:

• American Society of Microbiology  

• American Association for the Advancement of Science
   

Courses this year:

• Human Microbiology (Lecture and Lab) 

• Introduction to Public Health 

• Epidemiology 

• Global Health 

 Last Update:  15 October 2012 

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