Dr. Thomas Freeman

New breakthroughs

Drawing on our expertise and research, we serve the diverse needs of the community. Our faculty is dedicated to enabling students to use scientific approaches to discovery and understanding.
Measuring success

Our graduates go on to excel in a variety of graduate programs and professional schools. We take pride in seeing students succeed.
New breakthroughs

Drawing on our expertise and research, we serve the diverse needs of the community. Our faculty is dedicated to enabling students to use scientific approaches to discovery and understanding.

Dr. Thomas Freeman

Associate Professor

Office: 241 | Phone: (308) 865-8595 | Email: freemantl@unk.edu

Biography

Areas of Interest:

Morphology and condition indexes of diurnal raptors
Gender ratios of red-tailed hawks in Nebraska
Estimating raptor population density
Use of indexes (road counts) as valid estimators of density
Immune response to proteins modified by environmental exposures
Garlic mustard as an invasive species

Degrees:

B.S. (1991) - Texas Tech University, Wildlife Management
M.S. (1993) - Texas Tech University, Microbiology
PhD. (1996) - Texas Tech University, Biology

Professional Affiliations:

Dissertation & Thesis:

Freeman, T. L. 1996. Nucleotide sequence and regulation of the exuT complementing DNA of Erwinia chrysanthemi. Ph. D. Dissertation, Texas Tech University, Lubbock, Texas
Freeman, T. L. 1993. Cloning and characterization of the galacturonic acid uptake system in Erwinia chrysamhemi EC16. M. S. Thesis, Texas Tech University, Lubbock, Texas.

Schoenebeck, C. W., Turco, M., Fahrlander, R. M., Darveau, K. M., and Freeman, T. L. 2014. Sex and age group specific changes in body condition of red-tailed hawks in central Nebraska. The Wilson Journal of Ornithology 126(3):575-580.
Freeman, T. L. 2014. Diurnal raptors of Buffalo County Nebraska. The Prairie Naturalist 46:48-49.
Freeman, T. L. 2011. Monitoring the annual increase in garlic mustard in eastern Nebraska. Proceedings of the 22nd North American Prairie Conference. 2011. 22:146-147.
Freeman, T. L. 2010. Riparian forest associated with tall-grass prairie: species composition and distribution along the Missouri River of central Nebraska. North American Prairie Conference 21:63-68.
Duryee, M. J., Freeman, T. L., Willis, M. S., Hunter, C. D., Hamilton, B. C., Suzuki, H., Tuma, D. J., Klassen, L. W., Thiele, G. M. 2005. Scavenger receptors on sinusoidal liver endothelial cells (SECs) are involved in the uptake of aldehyde-modified proteins. Molecular Pharmacology 68(5):1423-1430.
Freeman, T. L., Haver, A., Duryee, M. J., Tuma, D. J., Klassen, L. W., Hamel. F. G., White, R. L., Rennard, S. I., & Thiele, G. M. 2005. Aldehydes in cigarette smoke react with the lipid peroxidation product malonaldehyde to form fluorescent protein adducts on lysines. Chemical Research in Toxicology 18(5):817-824.
Freeman, T. L., Tuma, D. J., Thiele, G. M., Klassen, L. W., Worrall, S., Niemela, O., Parkkila, S., Emery, P. & Preedy, V. R. 2005. Recent advances in alcohol-induced adduct formation. Alcoholism: Clinical and Experimental Research 29(7):1-7.
Thiele, G. M., Hill, G. E., Pavlik, J. A., Freeman, T. L., Tuma, D. J., Duryee, M. J., & Klassen, L. W. 2005. Halothane potentiates the alcohol-adduct induced TNF-alpha release in heart endothelial cells. BMC Anesthesiology 5(1):3.
Thiele, G. M., Duryee, M. J., Freeman, T. L., Sorrell, M. F., Willis, M. S., Tuma, D. J., & Klassen, L. W. 2005. Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol. Biochemical Pharmacology 70(11):1593-1600.
Duryee, M. J., Klassen, L. W., Freeman, T. L., Willis, M. S., Tuma, D. J., & Thiele, G. M. 2004. Lipopolysaccharide is a cofactor for malondialdehyde-acetaldehyde adduct-mediated cytokine/chemokine release by rat sinusoidal liver endothelial and kupffer cells. Alcoholism: Clinical and Experimental Research 28(12):1931-1938.
Duryee, M. J., Willis, M. S., Freeman, T. L., Kuszynski, C. A., Tuma, D. J., Klassen, L. W., & Thiele, G. M. 2004. Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity. Frontiers in Bioscience 9:3145-3155.
Freeman, T. L., Thiele, G. M., Klassen, L. W., Klassen, B. T., & Mailliard, M. E. 2004. N-(methylamino) isobutyric acid inhibits proliferation of CFSC-2C hepatic stellate cells. Biochemical Pharmacology 68:223–230.
Thiele, G. M., Freeman, T. L., & Klassen, L. W. 2004. Immunologic mechanisms of alcoholic liver injury. Seminars in Liver Disease 24(3):273-287.
Thiele, G. M., Duryee, M. J., Willis, M. S., Sorrell, M. F., Freeman, T. L., Tuma, D. J., & Klassen, L.W. 2004. Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells. Comparative Hepatology 14(3 Suppl 1):S25.
Duryee, M. J., Freeman, T. L., Willis, M. S., Tuma, D. J., & Klassen, L. W. 2003. Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells. Biochemical Pharmacology 66:1045-1054.
Freeman, T. L., Thiele, G. M., Tuma, D. J., Machu, T. K. & Mailliard, M. E. 2002. ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane. Archives of Biochemistry and Biophysics 400:215-222.
Freeman, T. L., Kharbanda, K. K., Tuma, D. J., & Mailliard, M. E. 2002. Inhibition of hepatic stellate cell collagen synthesis by N-(methylamino)isobutyric acid. Biochemical Pharmacology 63(4):697–706.
Zeitouni, N., Eubank, D. W., Lee, A. Q., Oxford, M. G., Freeman, T. L., Mailliard, M. E., & Beale, E. G. 2002. Phosphoenolpyruvate carboxykinase is induced in growth-arrested hepatoma cells. Biochemical and Biophysical Research Communications 290(5):1513-1520.
Freeman, T. L., & Mailliard, M. E. 2000. Post-transcriptional regulation of ATA2 transport during liver regeneration. Biochemical and Biophysical Research Communications 288:729-732.
Conrad, P. W., Freeman, T. L., Beitner-Johnson, D. & Millhorn, D. E. 1999. EPASItrans-Activation during hypoxia requires p42/p44 MAPK. Journal of Biological Chemistry 274(47):33709-33713.
Freeman, T. L., Ngo, H. Q., & Mailliard, M. E. 1999. Inhibition of system A amino acid transport and hepatocyte proliferation following partial hepatectomy in the rat. Hepatology 30(2):437-444.
Conforti, L., Kobayashi, S., Beitner-Johnson, D., Conrad, P. W., Freeman, T. L., & Millhorn, D. E. 1998. Regulation of gene expression and secretory functions in oxygen-sensing pheochromocytoma cells. Respiratory Physiology 115(2):249-260.
Haseloff, B. J., Freeman, T. L., Valmeekam, V., Melkus, M. W., Oner, F., Valachovic, M. S., & San Francisco, M. J. D. 1998. The exuT gene of Erwinia chrysanthemi EC 16: nucleotide sequence, expression, localization, and relevance of the gene product. MPMI 11(4):270-276.
Freeman, T. L., & San Francisco, M. J. 1994. Cloning of a galacturonic acid uptake gene from Erwinia chrysanthemi EC16. FEMS Microbiology Letters 118:101-106.